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Phosphoinositide 3-Kinase C2β Regulates RhoA and the Actin Cytoskeleton through an Interaction with Dbl

The regulation of cell morphology is a dynamic process under the control of multiple protein complexes acting in a coordinated manner. Phosphoinositide 3-kinases (PI3K) and their lipid products are widely involved in cytoskeletal regulation by interacting with proteins regulating RhoGTPases. Class I...

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Detalles Bibliográficos
Autores principales: Błajecka, Karolina, Marinov, Marin, Leitner, Laura, Uth, Kristin, Posern, Guido, Arcaro, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440356/
https://www.ncbi.nlm.nih.gov/pubmed/22984590
http://dx.doi.org/10.1371/journal.pone.0044945