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Cooperative Binding of Transcription Factors Promotes Bimodal Gene Expression Response

In the present work we extend and analyze the scope of our recently proposed stochastic model for transcriptional regulation, which considers an arbitrarily complex cis-regulatory system using only elementary reactions. Previously, we determined the role of cooperativity on the intrinsic fluctuation...

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Detalles Bibliográficos
Autores principales: Gutierrez, Pablo S., Monteoliva, Diana, Diambra, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440358/
https://www.ncbi.nlm.nih.gov/pubmed/22984566
http://dx.doi.org/10.1371/journal.pone.0044812