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Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation
Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system in which macrophages and microglia play a central role. Foamy macrophages and microglia, containing degenerated myelin, are abundantly found in active multiple sclerosis lesions. Recent studies have de...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440367/ https://www.ncbi.nlm.nih.gov/pubmed/22984598 http://dx.doi.org/10.1371/journal.pone.0044998 |