Cargando…

Differential Regulation of Transcription Factors by Location-Specific EGF Receptor Signaling via a Spatio-Temporal Interplay of ERK Activation

It is well established that EGFR signals from both the plasma membrane (PM) and endosome (EN). However, very little is known about whether and how the EGFR signals at the PM and EN to differentially regulate various signaling pathways and the physiological outcomes. In this communication, we establi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Peng, Wee, Ping, Jiang, Jennifer, Chen, Xinmei, Wang, Zhixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440385/
https://www.ncbi.nlm.nih.gov/pubmed/22984397
http://dx.doi.org/10.1371/journal.pone.0041354