The Crucial Role of Divalent Metal Ions in the DNA-Acting Efficacy and Inhibition of the Transcription of Dimeric Chromomycin A3

Chromomycin A3 (Chro) is capable of forming a stable dimeric complex via chelation with Ni(II), Fe(II) and Co(II). According to the circular dichroism study, the dimer conformations are significantly different among the Fe(II)-, Co(II)-, and Ni(II)-containing dimeric Chro complexes; however, the dim...

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Detalles Bibliográficos
Autores principales: Hsu, Chun-Wei, Chuang, Show-Mei, Wu, Wen-Ling, Hou, Ming-Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440418/
https://www.ncbi.nlm.nih.gov/pubmed/22984445
http://dx.doi.org/10.1371/journal.pone.0043792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440418/
https://www.ncbi.nlm.nih.gov/pubmed/22984445
http://dx.doi.org/10.1371/journal.pone.0043792

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