Intracellular Context Affects Levels of a Chemically Dependent Destabilizing Domain

The ability to regulate protein levels in live cells is crucial to understanding protein function. In the interest of advancing the tool set for protein perturbation, we developed a protein destabilizing domain (DD) that can confer its instability to a fused protein of interest. This destabilization...

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Detalles Bibliográficos
Autores principales: Sellmyer, Mark A., Chen, Ling-chun, Egeler, Emily L., Rakhit, Rishi, Wandless, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440426/
https://www.ncbi.nlm.nih.gov/pubmed/22984418
http://dx.doi.org/10.1371/journal.pone.0043297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440426/
https://www.ncbi.nlm.nih.gov/pubmed/22984418
http://dx.doi.org/10.1371/journal.pone.0043297

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