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Intracellular Context Affects Levels of a Chemically Dependent Destabilizing Domain
The ability to regulate protein levels in live cells is crucial to understanding protein function. In the interest of advancing the tool set for protein perturbation, we developed a protein destabilizing domain (DD) that can confer its instability to a fused protein of interest. This destabilization...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440426/ https://www.ncbi.nlm.nih.gov/pubmed/22984418 http://dx.doi.org/10.1371/journal.pone.0043297 |