The Prothrombotic Phenotypes in Familial Protein C Deficiency Are Differentiated by Computational Modeling of Thrombin Generation

The underlying cause of thrombosis in a large protein C (PC) deficient Vermont kindred appears to be multicausal and not explained by PC deficiency alone. We evaluated the contribution of coagulation factors to thrombin generation in this population utilizing a mathematical model that incorporates a...

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Detalles Bibliográficos
Autores principales: Brummel-Ziedins, Kathleen E., Orfeo, Thomas, Callas, Peter W., Gissel, Matthew, Mann, Kenneth G., Bovill, Edwin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440432/
https://www.ncbi.nlm.nih.gov/pubmed/22984498
http://dx.doi.org/10.1371/journal.pone.0044378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440432/
https://www.ncbi.nlm.nih.gov/pubmed/22984498
http://dx.doi.org/10.1371/journal.pone.0044378

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