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Low-Dose Rapamycin Treatment Increases the Ability of Human Regulatory T Cells to Inhibit Transplant Arteriosclerosis In Vivo

Regulatory T cells (T(reg)) are currently being tested in clinical trials as a potential therapy in cell and solid organ transplantation. The immunosuppressive drug rapamycin has been shown to preferentially promote T(reg) expansion. Here, we hypothesized that adjunctive rapamycin therapy might pote...

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Detalles Bibliográficos
Autores principales: Hester, J, Schiopu, A, Nadig, S N, Wood, K J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440570/
https://www.ncbi.nlm.nih.gov/pubmed/22500984
http://dx.doi.org/10.1111/j.1600-6143.2012.04065.x