Quantification of protein isoforms in mesenchymal stem cells by reductive dimethylation of lysines in intact proteins

Mass spectrometry (MS)-based quantification of highly homologous proteins in complex samples has proven difficult due to subtle sequence variations and the wide dynamic range of protein isoforms present. Herein, we report the use of reductive dimethylation on intact proteins to quantitatively compar...

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Detalles Bibliográficos
Autores principales: She, Yi-Min, Rosu-Myles, Michael, Walrond, Lisa, Cyr, Terry D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440571/
https://www.ncbi.nlm.nih.gov/pubmed/22144135
http://dx.doi.org/10.1002/pmic.201100308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440571/
https://www.ncbi.nlm.nih.gov/pubmed/22144135
http://dx.doi.org/10.1002/pmic.201100308

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