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Being Flexible: The Voltage-Controllable Activation Gate of Kv Channels
Kv channels form voltage-dependent potassium selective pores in the outer cell membrane and are composed out of four α-subunits, each having six membrane-spanning α-helices (S1–S6). The α-subunits tetramerize such that the S5–S6 pore domains co-assemble into a centrally located K(+) pore which is su...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440756/ https://www.ncbi.nlm.nih.gov/pubmed/22993508 http://dx.doi.org/10.3389/fphar.2012.00168 |