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Pre-clinical drug tests in the mdx mouse as a model of dystrophinopathies: an overview

Duchenne muscular dystrophy is a lethal X-linked muscle disease affecting 1/3500 live male birth. It results from defects in the subsarcolemmal protein dystrophin, a component of the dystrophinglycoprotein complex (DGC) which links the intracellular cytoskeleton to the extracellular matrix. The abse...

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Detalles Bibliográficos
Autor principal: DE LUCA, ANNAMARIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore SpA 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440805/
https://www.ncbi.nlm.nih.gov/pubmed/22655516