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Perfusion Flow Enhances Osteogenic Gene Expression and the Infiltration of Osteoblasts and Endothelial Cells into Three-Dimensional Calcium Phosphate Scaffolds

Maintaining cellular viability in vivo and in vitro is a critical issue in three-dimensional bone tissue engineering. While the use of osteoblast/endothelial cell cocultures on three-dimensional constructs has shown promise for increasing in vivo vascularization, in vitro maintenance of cellular via...

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Detalles Bibliográficos
Autores principales: Barron, Matthew J., Goldman, Jeremy, Tsai, Chung-Jui, Donahue, Seth W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440867/
https://www.ncbi.nlm.nih.gov/pubmed/22988460
http://dx.doi.org/10.1155/2012/915620