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Glibenclamide Administration Attenuates Infarct Volume, Hemispheric Swelling, and Functional Impairments following Permanent Focal Cerebral Ischemia in Rats

Studies from a single laboratory have shown that in rodent models of permanent stroke, administration of the sulfonylurea glibenclamide (Glib) is highly effective in reducing edema, mortality, and lesion volume. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends that new acute treatm...

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Detalles Bibliográficos
Autores principales: Wali, Bushra, Ishrat, Tauheed, Atif, Fahim, Hua, Fang, Stein, Donald G., Sayeed, Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440943/
https://www.ncbi.nlm.nih.gov/pubmed/22988544
http://dx.doi.org/10.1155/2012/460909