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Glibenclamide Administration Attenuates Infarct Volume, Hemispheric Swelling, and Functional Impairments following Permanent Focal Cerebral Ischemia in Rats
Studies from a single laboratory have shown that in rodent models of permanent stroke, administration of the sulfonylurea glibenclamide (Glib) is highly effective in reducing edema, mortality, and lesion volume. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends that new acute treatm...
Autores principales: | Wali, Bushra, Ishrat, Tauheed, Atif, Fahim, Hua, Fang, Stein, Donald G., Sayeed, Iqbal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440943/ https://www.ncbi.nlm.nih.gov/pubmed/22988544 http://dx.doi.org/10.1155/2012/460909 |
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