The EGF Receptor and HER2 Participate in TNF-α-Dependent MAPK Activation and IL-8 Secretion in Intestinal Epithelial Cells

TNF-α activates multiple mitogen-activated protein kinase (MAPK) cascades in intestinal epithelial cells (IECs) leading to the secretion of interleukin 8 (IL-8), a neutrophil chemoattractant and an angiogenic factor with tumor promoting properties. As the epidermal growth factor receptor (EGFR) is a...

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Detalles Bibliográficos
Autores principales: Jijon, Humberto B., Buret, Andre, Hirota, Christina L., Hollenberg, Morley D., Beck, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440955/
https://www.ncbi.nlm.nih.gov/pubmed/22988345
http://dx.doi.org/10.1155/2012/207398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440955/
https://www.ncbi.nlm.nih.gov/pubmed/22988345
http://dx.doi.org/10.1155/2012/207398

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