Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes

Phosphorylation of STAT3 (signal transducer and activator of transcription 3) is critical for its nuclear import and transcriptional activity. Although a shorter STAT3β spliceform was initially described as a negative regulator of STAT3α, gene knockout studies have revealed that both forms play crit...

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Detalles Bibliográficos
Autores principales: Ng, Ivan H. W., Ng, Dominic C. H., Jans, David A., Bogoyevitch, Marie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441131/
https://www.ncbi.nlm.nih.gov/pubmed/22799634
http://dx.doi.org/10.1042/BJ20120941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441131/
https://www.ncbi.nlm.nih.gov/pubmed/22799634
http://dx.doi.org/10.1042/BJ20120941

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