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Detecting pore-lining regions in transmembrane protein sequences

BACKGROUND: Alpha-helical transmembrane channel and transporter proteins play vital roles in a diverse range of essential biological processes and are crucial in facilitating the passage of ions and molecules across the lipid bilayer. However, the experimental difficulties associated with obtaining...

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Detalles Bibliográficos
Autores principales: Nugent, Timothy, Jones, David T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441209/
https://www.ncbi.nlm.nih.gov/pubmed/22805427
http://dx.doi.org/10.1186/1471-2105-13-169