Cargando…

Detecting pore-lining regions in transmembrane protein sequences

BACKGROUND: Alpha-helical transmembrane channel and transporter proteins play vital roles in a diverse range of essential biological processes and are crucial in facilitating the passage of ions and molecules across the lipid bilayer. However, the experimental difficulties associated with obtaining...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nugent, Timothy, Jones, David T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441209/ https://www.ncbi.nlm.nih.gov/pubmed/22805427 http://dx.doi.org/10.1186/1471-2105-13-169

Ejemplares similares

Transmembrane protein topology prediction using support vector machines
por: Nugent, Timothy, et al.
Publicado: (2009)

Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
por: Wang, Wuyang, et al.
Publicado: (2011)

Computational Design of Transmembrane Pores
por: Xu, Chunfu, et al.
Publicado: (2020)

Transmembrane helical interactions in the CFTR channel pore
por: Das, Jhuma, et al.
Publicado: (2017)

Regulation of Exocytotic Fusion Pores by SNARE Protein Transmembrane Domains
por: Wu, Zhenyong, et al.
Publicado: (2017)

Predicting Transmembrane Helix Packing Arrangements using Residue Contacts and a Force-Directed Algorithm
por: Nugent, Timothy, et al.
Publicado: (2010)

Assembly of transmembrane pores from mirror-image peptides
por: Krishnan R, Smrithi, et al.
Publicado: (2022)

Spatial positioning of CFTR’s pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathway
por: Gao, Xiaolong, et al.
Publicado: (2016)

Mathematical Characterization of Protein Transmembrane Regions
por: Roy Choudhury, Amrita, et al.
Publicado: (2013)

Prediction of Transmembrane Regions, Cholesterol, and Ganglioside Binding Sites in Amyloid-Forming Proteins Indicate Potential for Amyloid Pore Formation
por: Venko, Katja, et al.
Publicado: (2021)

Vitamin A Transport and the Transmembrane Pore in the Cell-Surface Receptor for Plasma Retinol Binding Protein
por: Zhong, Ming, et al.
Publicado: (2013)

Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes
por: Hoffman, Laura M., et al.
Publicado: (2020)

Direct Transmembrane Interaction between Actin and the Pore-Competent, Cholesterol-Dependent Cytolysin Pneumolysin
por: Hupp, Sabrina, et al.
Publicado: (2013)

Commentary Cystic Fibrosis Transmembrane Conductance Regulator : Permeant Ions Find the Pore
por: Dawson, David C., et al.
Publicado: (1997)

Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore
por: Couoh-Cardel, Sergio, et al.
Publicado: (2016)

Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains
por: Wu, Zhenyong, et al.
Publicado: (2016)

Confined Dynamics of Water in Transmembrane Pore of TRPV1 Ion Channel
por: Trofimov, Yury A., et al.
Publicado: (2019)

Transmembrane Epitope Delivery by Passive Protein Threading through the Pores of the OmpF Porin Trimer
por: Lee, Sejeong, et al.
Publicado: (2020)

PoreWalker: A Novel Tool for the Identification and Characterization of Channels in Transmembrane Proteins from Their Three-Dimensional Structure
por: Pellegrini-Calace, Marialuisa, et al.
Publicado: (2009)

Chemical modification of matrix porin from Escherichia coli: probing the pore topology of a transmembrane protein
Publicado: (1982)

Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores
por: Mudumbi, Krishna C., et al.
Publicado: (2020)

Bacterial Transmembrane Proteins that Lack N-Terminal Signal Sequences
por: Craney, Arryn, et al.
Publicado: (2011)

Single-channel SCAM Identifies Pore-lining Residues in the First Extracellular Loop and First Transmembrane Domains of Cx46 Hemichannels
por: Kronengold, J., et al.
Publicado: (2003)

High Transmembrane Voltage Raised by Close Contact Initiates Fusion Pore
por: Bu, Bing, et al.
Publicado: (2016)

Reconstitution of Ultrawide DNA Origami Pores in Liposomes for Transmembrane Transport of Macromolecules
por: Fragasso, Alessio, et al.
Publicado: (2021)

Re-Introduction of Transmembrane Serine Residues Reduce the Minimum Pore Diameter of Channelrhodopsin-2
por: Richards, Ryan, et al.
Publicado: (2012)

The Second Transmembrane Domain of P2X7 Contributes to Dilated Pore Formation
por: Sun, Chengqun, et al.
Publicado: (2013)

Ion access pathway to the transmembrane pore in P2X receptor channels
por: Kawate, Toshimitsu, et al.
Publicado: (2011)

Water Pores in Planar Lipid Bilayers at Fast and Slow Rise of Transmembrane Voltage
por: Maček Lebar, Alenka, et al.
Publicado: (2021)

Water Nanoconfined in a Hydrophobic Pore: Molecular Dynamics Simulations of Transmembrane Protein 175 and the Influence of Water Models
por: Lynch, Charlotte I., et al.
Publicado: (2021)

Length-Dependent Formation of Transmembrane Pores by 3(10)-Helical α-Aminoisobutyric Acid Foldamers
por: Jones, Jennifer E., et al.
Publicado: (2015)

Poisson-Nernst-Planck Models of Nonequilibrium Ion Electrodiffusion through a Protegrin Transmembrane Pore
por: Bolintineanu, Dan S., et al.
Publicado: (2009)

Pom33, a novel transmembrane nucleoporin required for proper nuclear pore complex distribution
por: Chadrin, Anne, et al.
Publicado: (2010)

MemDis: Predicting Disordered Regions in Transmembrane Proteins
por: Dobson, Laszlo, et al.
Publicado: (2021)

Accurate multiple sequence alignment of transmembrane proteins with PSI-Coffee
por: Chang, Jia-Ming, et al.
Publicado: (2012)

Conductance and amantadine binding of a pore formed by a lysine-flanked transmembrane domain of SARS coronavirus envelope protein
por: Torres, Jaume, et al.
Publicado: (2007)

Lah is a transmembrane protein and requires Spa10 for stable positioning of Woronin bodies at the septal pore of Aspergillus fumigatus
por: Leonhardt, Yannik, et al.
Publicado: (2017)

The Transmembrane Region Is Responsible for Targeting of Adaptor Protein LAX into “Heavy Rafts”
por: Hrdinka, Matous, et al.
Publicado: (2012)

Adaptive Threonine Increase in Transmembrane Regions of Mitochondrial Proteins in Higher Primates
por: Kitazoe, Yasuhiro, et al.
Publicado: (2008)

Oroxylin A Inhibits Hemolysis via Hindering the Self-Assembly of α-Hemolysin Heptameric Transmembrane Pore
por: Dong, Jing, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_9a7a0kd06hio455pgfv612jfun