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Using metagenomic analyses to estimate the consequences of enrichment bias for pathogen detection

BACKGROUND: Enriching environmental samples to increase the probability of detection has been standard practice throughout the history of microbiology. However, by its very nature, the process of enrichment creates a biased sample that may have unintended consequences for surveillance or resolving a...

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Detalles Bibliográficos
Autores principales: Pettengill, James B, McAvoy, Eugene, White, James R, Allard, Marc, Brown, Eric, Ottesen, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441234/
https://www.ncbi.nlm.nih.gov/pubmed/22839680
http://dx.doi.org/10.1186/1756-0500-5-378