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Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition
BACKGROUND: Pro-inflammatory stimuli, including cytokines like Interleukin-1β, Interleukin-6 and Interferon-γ, in the brain have been proposed to exacerbate existing Alzheimer’s disease (AD) neuropathology by increasing amyloidogenic processing of APP and promoting further Aβ accumulation in AD. On...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441281/ https://www.ncbi.nlm.nih.gov/pubmed/22838967 http://dx.doi.org/10.1186/1750-1326-7-36 |