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Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpression
BACKGROUND: Oxygen may damage the lung directly via generation of reactive oxygen species (ROS) or indirectly via the recruitment of inflammatory cells, especially neutrophils. Overexpression of extracellular superoxide dismutase (EC-SOD) has been shown to protect the lung against hyperoxia in the n...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441354/ https://www.ncbi.nlm.nih.gov/pubmed/22816678 http://dx.doi.org/10.1186/1465-9921-13-58 |