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Inhibitor of neuronal nitric oxide synthase improves gas exchange in ventilator-induced lung injury after pneumonectomy
BACKGROUND: Mechanical ventilation with high tidal volumes may cause ventilator-induced lung injury (VILI) and enhanced generation of nitric oxide (NO). We demonstrated in sheep that pneumonectomy followed by injurious ventilation promotes pulmonary edema. We wished both to test the hypothesis that...
Autores principales: | Suborov, Evgeny V, Smetkin, Alexey A, Kondratiev, Timofey V, Valkov, Andrey Y, Kuzkov, Vsevolod V, Kirov, Mikhail Y, Bjertnaes, Lars J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441363/ https://www.ncbi.nlm.nih.gov/pubmed/22720843 http://dx.doi.org/10.1186/1471-2253-12-10 |
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