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Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells

BACKGROUND: The classical view on eukaryotic gene expression proposes the scheme of a forward flow for which fluctuations in mRNA levels upon a stimulus contribute to determine variations in mRNA availability for translation. Here we address this issue by simultaneously profiling with microarrays th...

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Detalles Bibliográficos
Autores principales: Tebaldi, Toma, Re, Angela, Viero, Gabriella, Pegoretti, Ilaria, Passerini, Andrea, Blanzieri, Enrico, Quattrone, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441405/
https://www.ncbi.nlm.nih.gov/pubmed/22672192
http://dx.doi.org/10.1186/1471-2164-13-220