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Infrared optical imaging of matrix metalloproteinases (MMPs) up regulation following ischemia reperfusion is ameliorated by hypothermia

BACKGROUND: We investigated the use of a new MMP activatable probe MMPSense(™) 750 FAST (MMPSense750) for in-vivo visualization of early MMP activity in ischemic stroke. Following middle cerebral artery occlusion (MCAO) optical imaging was performed. Near-infrared (NIR) fluorescent images of MMPSens...

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Detalles Bibliográficos
Autores principales:	Barber, Philip A, Rushforth, David, Agrawal, Smriti, Tuor, Ursula I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441425/ https://www.ncbi.nlm.nih.gov/pubmed/22742423 http://dx.doi.org/10.1186/1471-2202-13-76

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