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Binding of Two Intrinsically Disordered Peptides to a Multi-Specific Protein: A Combined Monte Carlo and Molecular Dynamics Study

The unique ability of intrinsically disordered proteins (IDPs) to fold upon binding to partner molecules makes them functionally well-suited for cellular communication networks. For example, the folding-binding of different IDP sequences onto the same surface of an ordered protein provides a mechani...

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Detalles Bibliográficos
Autores principales: Staneva, Iskra, Huang, Yongqi, Liu, Zhirong, Wallin, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441455/
https://www.ncbi.nlm.nih.gov/pubmed/23028280
http://dx.doi.org/10.1371/journal.pcbi.1002682