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Influence of Tryptophan Contained in 1-Methyl-Tryptophan on Antimicrobial and Immunoregulatory Functions of Indoleamine 2,3-Dioxygenase

Indoleamine 2,3-dioxygenase (IDO) has been identified as an important antimicrobial and immunoregulatory effector molecule essential for the establishment of tolerance by regulating local tryptophan (Trp) concentrations. On the other hand, the immunosuppressive capacity of IDO can have detrimental e...

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Detalles Bibliográficos
Autores principales: Schmidt, Silvia K., Siepmann, Stephan, Kuhlmann, Katja, Meyer, Helmut E., Metzger, Sabine, Pudelko, Sabine, Leineweber, Margret, Däubener, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441469/
https://www.ncbi.nlm.nih.gov/pubmed/23028625
http://dx.doi.org/10.1371/journal.pone.0044797