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Influence of Tryptophan Contained in 1-Methyl-Tryptophan on Antimicrobial and Immunoregulatory Functions of Indoleamine 2,3-Dioxygenase
Indoleamine 2,3-dioxygenase (IDO) has been identified as an important antimicrobial and immunoregulatory effector molecule essential for the establishment of tolerance by regulating local tryptophan (Trp) concentrations. On the other hand, the immunosuppressive capacity of IDO can have detrimental e...
Autores principales: | Schmidt, Silvia K., Siepmann, Stephan, Kuhlmann, Katja, Meyer, Helmut E., Metzger, Sabine, Pudelko, Sabine, Leineweber, Margret, Däubener, Walter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441469/ https://www.ncbi.nlm.nih.gov/pubmed/23028625 http://dx.doi.org/10.1371/journal.pone.0044797 |
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