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Stochastic Simulations Suggest that HIV-1 Survives Close to Its Error Threshold
The use of mutagenic drugs to drive HIV-1 past its error threshold presents a novel intervention strategy, as suggested by the quasispecies theory, that may be less susceptible to failure via viral mutation-induced emergence of drug resistance than current strategies. The error threshold of HIV-1, [...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441496/ https://www.ncbi.nlm.nih.gov/pubmed/23028282 http://dx.doi.org/10.1371/journal.pcbi.1002684 |