Anti-Cancer Activity of a Novel Small Molecule Compound That Simultaneously Activates p53 and Inhibits NF-κB Signaling

The p53 and NF-κB pathways play important roles in diverse cellular functions, including cell growth, apoptosis, and tumorigenesis. Mutations that inactivate the p53 gene and constitutive NF-κB pathway activation are common occurrences in human cancers. Although many drugs are being developed that s...

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Detalles Bibliográficos
Autores principales: Hwang, Sun Gwan, Park, Jinah, Park, Joo Young, Park, Cheol Hyoung, Lee, Ki-Ho, Cho, Jeong Woo, Hwang, Jong-Ik, Seong, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441512/
https://www.ncbi.nlm.nih.gov/pubmed/23028510
http://dx.doi.org/10.1371/journal.pone.0044259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441512/
https://www.ncbi.nlm.nih.gov/pubmed/23028510
http://dx.doi.org/10.1371/journal.pone.0044259

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