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KCN1, a Novel Synthetic Sulfonamide Anticancer Agent: In Vitro and In Vivo Anti-Pancreatic Cancer Activities and Preclinical Pharmacology

The purpose of the present study was to determine the in vitro and in vivo anti-cancer activity and pharmacological properties of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, KCN1. In the present study, we investigated the in vitro activity of KCN1 on cell proli...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Ao, Lin, Rayburn, Elizabeth R., Xu, Hongxia, Zhang, Xiangrong, Zhang, Xu, Nag, Subhasree Ashok, Wu, Xuming, Wang, Ming-Hai, Wang, Hui, Van Meir, Erwin G., Zhang, Ruiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441526/
https://www.ncbi.nlm.nih.gov/pubmed/23028659
http://dx.doi.org/10.1371/journal.pone.0044883