Cargando…
KCN1, a Novel Synthetic Sulfonamide Anticancer Agent: In Vitro and In Vivo Anti-Pancreatic Cancer Activities and Preclinical Pharmacology
The purpose of the present study was to determine the in vitro and in vivo anti-cancer activity and pharmacological properties of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, KCN1. In the present study, we investigated the in vitro activity of KCN1 on cell proli...
Autores principales: | Wang, Wei, Ao, Lin, Rayburn, Elizabeth R., Xu, Hongxia, Zhang, Xiangrong, Zhang, Xu, Nag, Subhasree Ashok, Wu, Xuming, Wang, Ming-Hai, Wang, Hui, Van Meir, Erwin G., Zhang, Ruiwen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441526/ https://www.ncbi.nlm.nih.gov/pubmed/23028659 http://dx.doi.org/10.1371/journal.pone.0044883 |
Ejemplares similares
-
Preclinical Pharmacology of BA-TPQ, a Novel Synthetic Iminoquinone Anticancer Agent
por: Ezell, Scharri J., et al.
Publicado: (2010) -
Preclinical Evaluation of Anticancer Efficacy and Pharmacological Properties of FBA-TPQ, a Novel Synthetic Makaluvamine Analog
por: Zhang, Xiangrong, et al.
Publicado: (2012) -
Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure–Activity Relationships, and Molecular Mechanisms of Action
por: Nag, Subhasree Ashok, et al.
Publicado: (2012) -
Natural Product Ginsenoside 25-OCH(3)-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2
por: Wang, Wei, et al.
Publicado: (2012) -
The MDM2-p53 pathway revisited
por: Nag, Subhasree, et al.
Publicado: (2013)