Multiple Metabolic Alterations Exist in Mutant PI3K Cancers, but Only Glucose Is Essential as a Nutrient Source

Targeting tumour metabolism is becoming a major new area of pharmaceutical endeavour. Consequently, a systematic search to define whether there are specific energy source dependencies in tumours, and how these might be dictated by upstream driving genetic mutations, is required. The PI3K-AKT-mTOR si...

Descripción completa

Detalles Bibliográficos
Autores principales: Foster, Rebecca, Griffin, Sue, Grooby, Suzanne, Feltell, Ruth, Christopherson, Cindy, Chang, Monica, Sninsky, John, Kwok, Shirley, Torrance, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441563/
https://www.ncbi.nlm.nih.gov/pubmed/23028762
http://dx.doi.org/10.1371/journal.pone.0045061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441563/
https://www.ncbi.nlm.nih.gov/pubmed/23028762
http://dx.doi.org/10.1371/journal.pone.0045061

Ejemplares similares