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Multiple Metabolic Alterations Exist in Mutant PI3K Cancers, but Only Glucose Is Essential as a Nutrient Source

Targeting tumour metabolism is becoming a major new area of pharmaceutical endeavour. Consequently, a systematic search to define whether there are specific energy source dependencies in tumours, and how these might be dictated by upstream driving genetic mutations, is required. The PI3K-AKT-mTOR si...

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Detalles Bibliográficos
Autores principales:	Foster, Rebecca, Griffin, Sue, Grooby, Suzanne, Feltell, Ruth, Christopherson, Cindy, Chang, Monica, Sninsky, John, Kwok, Shirley, Torrance, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441563/ https://www.ncbi.nlm.nih.gov/pubmed/23028762 http://dx.doi.org/10.1371/journal.pone.0045061

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