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Hepcidin Regulation by BMP Signaling in Macrophages Is Lipopolysaccharide Dependent

Hepcidin is an antimicrobial peptide, which also negatively regulates iron in circulation by controlling iron absorption from dietary sources and iron release from macrophages. Hepcidin is synthesized mainly in the liver, where hepcidin is regulated by iron loading, inflammation and hypoxia. Recentl...

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Detalles Bibliográficos
Autores principales: Wu, Xinggang, Yung, Lai-Ming, Cheng, Wai-Hang, Yu, Paul B., Babitt, Jodie L., Lin, Herbert Y., Xia, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441567/
https://www.ncbi.nlm.nih.gov/pubmed/23028567
http://dx.doi.org/10.1371/journal.pone.0044622