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Hepcidin Regulation by BMP Signaling in Macrophages Is Lipopolysaccharide Dependent
Hepcidin is an antimicrobial peptide, which also negatively regulates iron in circulation by controlling iron absorption from dietary sources and iron release from macrophages. Hepcidin is synthesized mainly in the liver, where hepcidin is regulated by iron loading, inflammation and hypoxia. Recentl...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441567/ https://www.ncbi.nlm.nih.gov/pubmed/23028567 http://dx.doi.org/10.1371/journal.pone.0044622 |