Slc15a4, a Gene Required for pDC Sensing of TLR Ligands, Is Required to Control Persistent Viral Infection

Plasmacytoid dendritic cells (pDCs) are the major producers of type I IFN in response to viral infection and have been shown to direct both innate and adaptive immune responses in vitro. However, in vivo evidence for their role in viral infection is lacking. We evaluated the contribution of pDCs to...

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Detalles Bibliográficos
Autores principales: Blasius, Amanda L., Krebs, Philippe, Sullivan, Brian M., Oldstone, Michael B., Popkin, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441671/
https://www.ncbi.nlm.nih.gov/pubmed/23028315
http://dx.doi.org/10.1371/journal.ppat.1002915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441671/
https://www.ncbi.nlm.nih.gov/pubmed/23028315
http://dx.doi.org/10.1371/journal.ppat.1002915

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