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A Genetic and Pathologic Study of a DENV2 Clinical Isolate Capable of Inducing Encephalitis and Hematological Disturbances in Immunocompetent Mice

Dengue virus (DENV) is the causative agent of dengue fever (DF), a mosquito-borne illness endemic to tropical and subtropical regions. There is currently no effective drug or vaccine formulation for the prevention of DF and its more severe forms, i.e., dengue hemorrhagic fever (DHF) and dengue shock...

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Detalles Bibliográficos
Autores principales: Amorim, Jaime Henrique, Pereira Bizerra, Raíza Sales, dos Santos Alves, Rúbens Prince, Sbrogio-Almeida, Maria Elisabete, Levi, José Eduardo, Capurro, Margareth Lara, de Souza Ferreira, Luís Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441697/
https://www.ncbi.nlm.nih.gov/pubmed/23028722
http://dx.doi.org/10.1371/journal.pone.0044984