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The Legionella IcmSW Complex Directly Interacts with DotL to Mediate Translocation of Adaptor-Dependent Substrates

Legionella pneumophila is a Gram-negative bacterium that replicates within human alveolar macrophages by evasion of the host endocytic pathway through the formation of a replicative vacuole. Generation of this vacuole is dependent upon the secretion of over 275 effector proteins into the host cell v...

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Detalles Bibliográficos
Autores principales: Sutherland, Molly C., Nguyen, Thuy Linh, Tseng, Victor, Vogel, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441705/
https://www.ncbi.nlm.nih.gov/pubmed/23028312
http://dx.doi.org/10.1371/journal.ppat.1002910