C. elegans SIRT6/7 Homolog SIR-2.4 Promotes DAF-16 Relocalization and Function during Stress

FoxO transcription factors and sirtuin family deacetylases regulate diverse biological processes, including stress responses and longevity. Here we show that the Caenorhabditis elegans sirtuin SIR-2.4—homolog of mammalian SIRT6 and SIRT7 proteins—promotes DAF-16–dependent transcription and stress-in...

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Detalles Bibliográficos
Autores principales: Chiang, Wei-Chung, Tishkoff, Daniel X., Yang, Bo, Wilson-Grady, Joshua, Yu, Xiaokun, Mazer, Travis, Eckersdorff, Mark, Gygi, Steven P., Lombard, David B., Hsu, Ao-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441721/
https://www.ncbi.nlm.nih.gov/pubmed/23028355
http://dx.doi.org/10.1371/journal.pgen.1002948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441721/
https://www.ncbi.nlm.nih.gov/pubmed/23028355
http://dx.doi.org/10.1371/journal.pgen.1002948

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