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Doxorubicin Induces Cytotoxicity through Upregulation of pERK–Dependent ATF3
Although doxorubicin is commonly used in the treatment of many cancer types, its use in chemotherapy has been limited, largely because of its severe side effects, including cardiotoxicity and nephrotoxicity. In this study, we aimed to identify the mechanism of doxorubicin-induced cytotoxicity by usi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441731/ https://www.ncbi.nlm.nih.gov/pubmed/23028726 http://dx.doi.org/10.1371/journal.pone.0044990 |