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A Cell Culture Adapted HCV JFH1 Variant That Increases Viral Titers and Permits the Production of High Titer Infectious Chimeric Reporter Viruses

The unique properties of the hepatitis C virus (HCV) JFH1 isolate have made it possible to produce and study HCV in an infectious cell culture system. However, relatively low virus titers restrict some of the uses of this system and preparing infectious chimeric reporter viruses have been difficult....

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Detalles Bibliográficos
Autores principales: Liu, Shuanghu, Xiao, Li, Nelson, Cassie, Hagedorn, Curt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441746/
https://www.ncbi.nlm.nih.gov/pubmed/23028707
http://dx.doi.org/10.1371/journal.pone.0044965