Phase Variable O Antigen Biosynthetic Genes Control Expression of the Major Protective Antigen and Bacteriophage Receptor in Vibrio cholerae O1

The Vibrio cholerae lipopolysaccharide O1 antigen is a major target of bacteriophages and the human immune system and is of critical importance for vaccine design. We used an O1-specific lytic bacteriophage as a tool to probe the capacity of V. cholerae to alter its O1 antigen and identified a novel...

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Detalles Bibliográficos
Autores principales: Seed, Kimberley D., Faruque, Shah M., Mekalanos, John J., Calderwood, Stephen B., Qadri, Firdausi, Camilli, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441752/
https://www.ncbi.nlm.nih.gov/pubmed/23028317
http://dx.doi.org/10.1371/journal.ppat.1002917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441752/
https://www.ncbi.nlm.nih.gov/pubmed/23028317
http://dx.doi.org/10.1371/journal.ppat.1002917

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