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Phase Variable O Antigen Biosynthetic Genes Control Expression of the Major Protective Antigen and Bacteriophage Receptor in Vibrio cholerae O1
The Vibrio cholerae lipopolysaccharide O1 antigen is a major target of bacteriophages and the human immune system and is of critical importance for vaccine design. We used an O1-specific lytic bacteriophage as a tool to probe the capacity of V. cholerae to alter its O1 antigen and identified a novel...
Autores principales: | Seed, Kimberley D., Faruque, Shah M., Mekalanos, John J., Calderwood, Stephen B., Qadri, Firdausi, Camilli, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441752/ https://www.ncbi.nlm.nih.gov/pubmed/23028317 http://dx.doi.org/10.1371/journal.ppat.1002917 |
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