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Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
BACKGROUND: The human genome contains a large amount of cis-regulatory DNA elements responsible for directing both spatial and temporal gene-expression patterns. Previous studies have shown that based on their mRNA expression breast tumors could be divided into five subgroups (Luminal A, Luminal B,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441847/ https://www.ncbi.nlm.nih.gov/pubmed/22616941 http://dx.doi.org/10.1186/1471-2164-13-199 |