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Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes

BACKGROUND: The human genome contains a large amount of cis-regulatory DNA elements responsible for directing both spatial and temporal gene-expression patterns. Previous studies have shown that based on their mRNA expression breast tumors could be divided into five subgroups (Luminal A, Luminal B,...

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Detalles Bibliográficos
Autores principales:	Joshi, Himanshu, Nord, Silje H, Frigessi, Arnoldo, Børresen-Dale, Anne-Lise, Kristensen, Vessela N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441847/ https://www.ncbi.nlm.nih.gov/pubmed/22616941 http://dx.doi.org/10.1186/1471-2164-13-199

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