Genetic Analysis of Rare Disorders: Bayesian Estimation of Twin Concordance Rates

Twin concordance rates provide insight into the possibility of a genetic background for a disease. These concordance rates are usually estimated within a frequentistic framework. Here we take a Bayesian approach. For rare diseases, estimation methods based on asymptotic theory cannot be applied due...

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Detalles Bibliográficos
Autores principales: van den Berg, Stéphanie M., Hjelmborg, Jacob vB.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442174/
https://www.ncbi.nlm.nih.gov/pubmed/22711379
http://dx.doi.org/10.1007/s10519-012-9547-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442174/
https://www.ncbi.nlm.nih.gov/pubmed/22711379
http://dx.doi.org/10.1007/s10519-012-9547-9

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