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Genetic Analysis of Rare Disorders: Bayesian Estimation of Twin Concordance Rates
Twin concordance rates provide insight into the possibility of a genetic background for a disease. These concordance rates are usually estimated within a frequentistic framework. Here we take a Bayesian approach. For rare diseases, estimation methods based on asymptotic theory cannot be applied due...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442174/ https://www.ncbi.nlm.nih.gov/pubmed/22711379 http://dx.doi.org/10.1007/s10519-012-9547-9 |