MOZ Regulates the Tbx1 Locus, and Moz Mutation Partially Phenocopies DiGeorge Syndrome

DiGeorge syndrome, caused by a 22q11 microdeletion or mutation of the TBX1 gene, varies in severity greatly, even among monozygotic twins. Epigenetic phenomena have been invoked to explain phenotypic differences in individuals of identical genetic composition, although specific chromatin modificatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Voss, Anne K., Vanyai, Hannah K., Collin, Caitlin, Dixon, Mathew P., McLennan, Tamara J., Sheikh, Bilal N., Scambler, Peter, Thomas, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442180/
https://www.ncbi.nlm.nih.gov/pubmed/22921202
http://dx.doi.org/10.1016/j.devcel.2012.07.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442180/
https://www.ncbi.nlm.nih.gov/pubmed/22921202
http://dx.doi.org/10.1016/j.devcel.2012.07.010

Ejemplares similares