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Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation

Stefin B (cystatin B) is an endogenous inhibitor of cysteine proteinases localized in the nucleus and the cytosol. Loss-of-function mutations in the stefin B gene (CSTB) gene were reported in patients with Unverricht-Lundborg disease (EPM1). Our previous results showed that thymocytes isolated from...

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Detalles Bibliográficos
Autores principales: Sun, Tao, Turk, Vito, Turk, Boris, Kopitar-Jerala, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442183/
https://www.ncbi.nlm.nih.gov/pubmed/23049497
http://dx.doi.org/10.3389/fnmol.2012.00093